Creative Writer Long Term Pharmacokinetic Studies Typically, drugs have a relatively short half-life. Every once in a while, a drug will be under development that has a significantly longer half-life than the norm. These “unicorn” compounds might be ... Apr 14, 2021
Creative Writer Safety Pharmacology at Attentive Science Safety Pharmacology assessments have been a required component of the IND submission package since 2001 per ICH guidelines S7A/B. These studies are designed to tease out the potential for adverse... Mar 24, 2021
Creative Writer Maximum Tolerated Dose (MTD) Studies Maximum Tolerated Dose (MTD) studies are among one of the earliest opportunities to administer your compound to a living test system, in order to determine potential signs of toxicity. Establishing th... Mar 10, 2021
Creative Writer Subchronic Toxicology Studies from Attentive Subchronic toxicology studies are regulatory driven studies necessary to properly assess the toxicity and toxicokinetic profile of your compound that will be used to establish equivalent doses on your... Feb 25, 2021
Creative Writer High Throughput Non-Rodent In-Vivo PK Your compounds that are destined for success and ultimately reaching your intended target population need to blossom. Eliminating compounds that have less desirable and/or poor In-Vivo Pharmacokinetic... Feb 10, 2021
Creative Writer Dose Range Finding Studies From Attentive When working with an experienced lab, Dose Range Finding (DRF) studies are used as an early detection warning system for your compound. Typically in DRF studies we are pushing dose levels to identify... Jan 27, 2021
Creative Writer Continuing Collaboration, Oversight and Accountability You have spent time and money developing a compound and selecting a contract research lab to help develop that compound into a marketable therapy. You are now at the point where you have to hand that ... Jan 13, 2021
Creative Writer IND Enabling Studies from Attentive Science Investigational New Drug (IND) enabling studies are a matrix of tests that must be conducted before a new therapeutic can be administered to the intended population. Depending on the results of each I... Dec 15, 2020
Creative Writer Discovery Toxicology and Pharmacokinetic Services from Attentive Science Attentive offers Discovery Toxicology [1] and Pharmacokinetic [2] services amongst other non-clinical services. We partner with our clients during the early phase of Discovery to assess exposure ... Nov 24, 2020
Creative Writer Attentive's Client-Calibrated Approach * How does the industry increase efficiency? * * Attentive has been asked this question over and over again and we came up with our Client Calibrated Approach. Quite simply, this approach allo... Oct 29, 2020
Creative Writer High Throughput PK Formulation Screening Attentive Science offers a service to solve one of our client’s biggest challenges: High Throughput PK Formulation Screening. When a client has developed a novel molecule that is going to be used to t... Oct 16, 2020
Creative Writer State of the ART Technology Anytime we meet a new client, there are a number of questions they have in order to “check the boxes” in terms of their standard expectations of our abilities as a nonclinical contract research labora... Sep 29, 2020