Creative Writer Advantages of a Boutique CRO There are three basic parameters that may influence your decision to work with a Nonclinical CRO, whether that be a single PK study or placing an IND-program. Price, timing, and most importantly, qual... Sep 15, 2021
Creative Writer Companion Animal Safety Assessments Attentive Science has been providing early discovery toxicology, formulation/PK screening studies, MTD/Subchronic toxicity studies as well as Safety Pharmacology services to the biotechnology and phar... Aug 30, 2021
Creative Writer You are invited to join us on a tour. The CDC just last week recommended the wearing of masks indoors again in places with high Covid-19 transmission rates. You and I have been lucky to live through the height of the pandemic and we are g... Aug 10, 2021
Creative Writer Let's Take a Breath and Discuss Something... A previous blog from Attentive Science provided an overview of the core battery Safety Pharmacology assessments required prior to first administration of new drugs to humans. In this issue we will dis... Jul 13, 2021
Creative Writer In-vivo Cardiovascular Safety (CV) Assessments from Attentive Science A crucial regulatory step for development and approval of test substances that have high systemic exposure is Safety Pharmacology. Prior to phase I clinical trials, the effects of a therapeutic on the... Jun 25, 2021
Creative Writer Go to the front of the line - with Attentive Post the “Covid 19 lockdown state of affairs” of 2020 we have seen that many of the companies for whom we provide services are looking to return to “normal” situations with regards to drug development... Jun 13, 2021
Creative Writer Program Timelines at Attentive Science The quality and scientific expertise of veterans at Attentive Science remains unquestionable for Pharmacokinetics, Toxicology and Safety Pharmacology. Another very important attribute required in our ... May 29, 2021
Creative Writer CNS Safety Pharmacology Services from Attentive Science A previous blog from Attentive Science provided an overview of the core battery Safety Pharmacology assessments required prior to first administration of new drugs to humans. In this issue we will dis... May 15, 2021
Creative Writer ...to SEND or not to SEND... Recent expedited U.S. Food & Drug Administration (FDA) review in response to our public health emergency demonstrates efficiencies that can be attained with true implementation of standardized data. I... Apr 30, 2021
Creative Writer Long Term Pharmacokinetic Studies Typically, drugs have a relatively short half-life. Every once in a while, a drug will be under development that has a significantly longer half-life than the norm. These “unicorn” compounds might be ... Apr 12, 2021
Creative Writer Safety Pharmacology at Attentive Science Safety Pharmacology assessments have been a required component of the IND submission package since 2001 per ICH guidelines S7A/B. These studies are designed to tease out the potential for adverse even... Mar 29, 2021
Creative Writer Maximum Tolerated Dose (MTD) Studies Maximum Tolerated Dose (MTD) studies are among one of the earliest opportunities to administer your compound to a living test system, in order to determine potential signs of toxicity. Establishing th... Mar 11, 2021